The Officers of Cancer Research And Biostatistics bring a myriad of skills and talents honed through years of experience conducting cancer research in SWOG and with pharmaceutical partners, in service, and as entrepreneurs. Collectively they oversee the day to day running of the company, and have a role in the management of the research and teams doing the research.
To see biographical information please click on a name below.
John Crowley, Ph.D.
President and Chief Executive Officer
John Crowley, Ph.D., brings four decades of experience in Biostatistics to his role as President and CEO of Cancer Research And Biostatistics (CRAB). Dr. Crowley was the Director of the Statistical Center for the SWOG, co-located at CRAB and the Fred Hutchinson Cancer Research Center from 1984 to 2012. Building on that expertise, under Dr. Crowley’s lead CRAB also serves as the Statistical Center for the Myeloma Institute for Research and Therapy at the University of Arkansas for Medical Sciences, the Stand Up to Cancer Pancreatic dream team; CRAB also works intimately with the Pancreatic Cancer Research Team, the International Association for the Study of Lung Cancer, the International Myeloma Foundation and Sarcoma Alliance Research Through Collaboration. Read more about these research groups in Our Key Partnerships.
To serve these groups, Dr. Crowley oversees the study design, protocol development, data management, quality control, data analysis, and statistical research of more than 130 active multi-site clinical cancer trials. Dr. Crowley manages a staff of 85 high-level statisticians, data coordinators, application developers and other professionals dedicated to conquering cancer through large-scale clinical trials. Dr. Crowley's own research interests focus on the design and analysis of cancer clinical and translation trials. His more recent research focuses on analytical methods for utilizing microarray data to determine predictive and prognostic groups; the design of targeted therapy trials; and methods for describing staging systems for lung cancer and myeloma. His longstanding interest in developing exploratory tools for survival data has produced widely used statistical applications in these areas. Dr. Crowley also educates cancer clinicians and biostatisticians here and abroad in the principles and pitfalls of cancer clinical trials.
Since Dr. Crowley's research career began in 1974, he has had numerous significant accomplishments. He served as Head of the Biostatistics Program at the Fred Hutchinson Cancer Research Center from 1983 until 1993, during which time he was honored with a Mortimer Spiegelman Award, given every year by the American Public Health Association to an outstanding young biostatistician. Dr. Crowley's credentials also include prestigious fellowships from the American Statistical Association and the American Association for the Advancement of Science. To date he has authored over 250 professional papers and books.
Dr. Crowley received his master’s and doctorate degrees (in 1970 and 1973, respectively) in Biomathematics from the University of Washington. He served as a Postdoctoral Fellow at Stanford University and then moved on to an Assistant Professorship in 1974, followed by an Associate Professorship in 1979, at the University of Wisconsin Departments of Human Oncology and Statistics. In 1982 Dr. Crowley accepted an appointment as Associate Member at the Fred Hutchinson Cancer Research Center (FHCRC) along with an Associate Professorship in Biostatistics at the University of Washington. He was subsequently promoted to Full Professor at the University and Full Member at FHCRC in 1984. His academic base is now at CRAB, and he holds a joint appointment at the Full Member level at FHCRC. John is an avid sports fan, enjoys traveling, hiking, bird watching and an occasional game of tennis.
Evonne Lackey, C.C.R.P.
First Vice President and Chief Data Management Officer
Evonne Lackey, C.C.R.P., brings 25 years of experience in oncology data management to Cancer Research And Biostatistics. She has oversight for the prevention and therapeutic data management activities associated with SWOG, one of the largest of the National Cancer Institute sponsored cancer clinical trial cooperative groups. She also provides data management expertise and resources for CRAB’s partner research groups. She has been instrumental in moving data management from paper based to proprietary based data systems to commercially available data collection platforms. She provides guidance to the design of electronic data capture forms, edit check requirements, and registration and randomization procedures. Her focus on quality data collection and review assists the biostatisticians with timely data for analysis.
Ms. Lackey began her career as a data manager at a large military hospital providing support for the numerous physicians who actively participated in oncology clinical research trials. She went on to assist in the establishment of one of the National Cancer Institute's premier Community Clinical Oncology Programs in the Pacific Northwest. In 1984, she was hired by the Fred Hutchinson Cancer Research Center (FHCRC) at the SWOG Statistical Center. She has a two-year degree in Business Administration and she is a Certified Clinical Research Professional through the Society of Clinical Research Associates (SoCRA).
Evonne enjoys traveling to warm climates in cold weather, spending time at the ocean where the terrain is flat enough for long walks and bike rides, cooking and reading.
Antje Hoering, Ph.D.
Vice President, Chief Scientific Officer
Antje Hoering, Ph.D, Vice President and Chief Scientific Officer, has a unique and comprehensive background in applied and methodological research in biostatistics, encompassing areas such as the design and analysis of oncology clinical trials, as well as the analysis of a wide variety of correlative data. Dr. Hoering leads the CRAB statistics team, comprising of more than 10 MS and PhD statisticians as well as a SAS programmer with diverse backgrounds. Dr. Hoering is the lead statistician of the SWOG Myeloma Committee and the SWOG Early Therapeutics Subcommittee. She is the co-director of the biostatistics core of the Sarcoma SARC SPORE and serves as coordinating statistician for the Myeloma Institute for Research and Therapy, where CRAB serves as the Biostatistics Core of a Program Project grant. Dr. Hoering also serves as a consultant on a variety of industry sponsored studies, including a phase III registration trial and has been the biostatistics representative on two Type B meetings with the FDA. Dr. Hoering holds affiliate appointments at the Fred Hutchinson Cancer Research Center and the Biostatistics Department of the University of Washington.
William S. Charters, M.B.A.
Vice President, Treasurer, Chief Financial Officer
William Charters, Chief Financial Officer, guides the fiscal direction of CRAB while it seeks to expand current and future collaborations with cancer centers, clinical research consortia, private industry, and non-profit groups involved in oncology clinical trials. Mr. Charters acts as a liaison with the Board of Directors, and oversees the development and maintenance of CRAB's strategic plan.
Mr. Charters comes to CRAB with 30 years of comprehensive experience in leadership and business operations developed within the contract research organization, Battelle where he served as financial manager implementing financial and operational initiatives in support of strategic objectives focused on improving public health and data analytics, working with government and commercial clients to accelerate innovation in health and life sciences. Mr. Charters holds an MBA from the Gonzaga University School of Business. Mr. Charters applies business management and analysis skills to research operations. Most recently, Mr. Charters was the Finance Manager for Battelle’s Health and Analytics business unit, where he lead center business activities; implemented operational plans and budgets, monitored financial metrics and key indicators to achieve financial objectives.
Mr. Charters earned his bachelor’s in Business Administration from Seattle University and holds an MBA from the Gonzaga University School of Business.
Mr. Charters enjoys traveling with his wife Marcie and other activities, including fly-fishing, skiing, rowing, and furniture-building. He is a member of Western Rivers Conservancy and Lake Union Crew.
Keith Goodman, D.B.A.
Vice President, Chief Technology Officer
Keith Goodman, D.B.A., Vice President and Chief Technology Officer, leads the Applications Development and Information Technology departments in the development of cutting-edge data capture solutions and the support of technology services that ensure the availability and protection of clinical trial data. Dr. Goodman joined CRAB in November 2005 and has served as CTO since January 2008 when he became a member of the management team.
Dr. Goodman has more than 23 years of experience in computer technology, including roles in application development, business management, and computer systems support. His expertise in software development and corporate management is honed from 10 years in leading his own software development company, NRSPACE Software, which was focused on the creation of applications focused on training nurses and healthcare technicians. His business also provided computer technology consulting to small- to medium-sized businesses in the Seattle area. Following an initial career as a journalist when he also became the ad-hoc computer technician, his technology career formally began at the Fred Hutchinson Cancer Research Center where he spent five years in support of research computer systems.
Dr. Goodman holds a Doctorate in Business Administration from Argosy University/Seattle and Bachelor’s and Master’s degrees in Communications from the University of Washington. His research interest is in automating the capture of data from the electronic medical record for use in in multisite cancer clinical trials. Keith enjoys reading for personal growth and pleasure, traveling, hiking, fishing, and watching and coaching baseball.
Tammy Buist, B.A., M.B.A.
Vice President, Secretary, Chief Business Officer
As the Chief Business Officer of CRAB, Ms. Buist oversees the HR, Administrative, Contracts & Grants and Compliance groups. As one of the senior officers of CRAB, Ms. Buist is a valuable and integral member of the team. She contributes pharmaceutical, biotechnology, venture capital and consulting experience in the cancer field including cancer therapeutics and cancer diagnostics.
Before joining CRAB, Ms. Buist was founder and CEO of Phoenix, Inc., a management consulting firm specializing in biotechnology. She has been a founder or executive team member of four start-up biotechnology companies including Tekmira Pharmaceuticals, Epigenomics, Targeted Growth and AnorMED. She has worked in the life sciences arena for several decades spanning a range of technologies including RNAi, epigenetics, and crop biotechnology. She has a keen business sense with seasoned finance, business development, scientific and strategic expertise.
Ms. Buist is a member of the Licensing Executive Society. Ms. Buist has served on the Board of Expanding Your Horizons (EYH), a non-profit organization dedicated to increasing technology awareness among young women. She has served as a regular volunteer at a Seattle homeless shelter, and she is involved in supporting the Technology Access Foundation.
Ms. Buist has an M.B.A. from the Massachusetts Institute of Technology specializing in finance and human resource management. She holds a B.A. in Chemistry from Whitman College.