News & Events

​CRAB Scientists Presented at Clinical Trials Training Course

Antje Hoering and John Crowley presented at a training workshop in integrative oncology research hosted by Cancer Treatment Centers of America CTCA at the Western Regional Medical Center in Phoenix, AZ on Friday and Saturday, April 24-25, 2015. Drs. Hoering and Crowley gave talks on Phase I and II clinical trials and help with protocol development and related statistical considerations.

CRAB has collaborated with CTCA since 2013 on training workshops. John and Antje are proud to continue this work with CTCA.


For Immediate Release - Launch of Project Survival℠: Collaboration Aims to Uncover First Ever Biomarker for Pancreatic Cancer

Berg, BIDMC Cancer Center, CRAB/Pancreatic Cancer Research Team work together to eradicate disease

BOSTON, April 7, 2015 – The search to discover and validate the first-ever clinical biomarker to diagnose and treat pancreatic cancer is at the foundation of a new, cross-sector collaboration. Berg, a biopharmaceutical company committed to uncovering health solutions through a data-driven, biological research approach; the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC), a Harvard Medical School teaching hospital, and the Pancreatic Cancer Research Team (PCRT) managed by Cancer Research And Biostatistics (CRAB) announced today they will work together to eradicate the disease.

According to The National Cancer Institute, nearly 47,000 Americans were diagnosed with pancreatic cancer in 2014, a disease from which only 6.7 percent will survive five years. "Pancreatic cancer will become the No. 2 cause of cancer death in the United States within five years, surpassing both breast and colon cancer," said James Moser, MD, director of the research team for BIDMC's new Pancreas and Liver Institute and an Associate Professor of Surgery at Harvard Medical School.

"Finding a new biomarker will bring real hope to patients with pancreatic cancer. Currently, 70 percent of people with even the smallest pancreatic tumors pass up potentially life-saving treatments. We believe that our new collaboration with Berg and the Pancreatic Cancer Research Team represents the dawn of the kind of precision medicine needed to beat this terrible disease."

You may access the full press release via this PDF.


CRAB Founder Speaks at the SCT Annual Meeting and a Memorial to Marvin Zelen

John Crowley, PhD and Chief of Strategic Alliances at Cancer Research And Biostatistics (CRAB), will participate in a session at the Society for Clinical Trials (SCT) Annual Meeting on May 18, 2015. The session, titled "Recipe to becoming a successful biostatistician in a collaborative environment", will focus on successful career development and leadership. Mentoring, communication and project management strategies will be discussed by Dr. Crowley and a panel of three other speakers.

Dr. Crowley will also give an invited talk at the SCT's memorial session for Dr. Marvin Zelen. Dr. Crowley will discuss Dr. Zelen's contributions to cancer clinical trials and his influence on Dr. Crowley's own work.

John Crowley is the Founder and until 2014 the Chief Executive Officer of CRAB, a nonprofit research organization dedicated to helping conquer cancer. He received his PhD in Biomathematics from the University of Washington, and has had faculty appointments at the University of Wisconsin, the University of Washington and the Fred Hutchinson Cancer Research Center.


Co-founder Dr. Catherine Crowley Moves on to “Other Duties”

CRAB co-founder Dr. Catherine Crowley has decided to pursue a new chapter in her life. After 16 years in leadership, Cay retired from CRAB at the end of December.

Dr. Cay Crowley joined her husband, Dr. John Crowley, in founding CRAB in 1997 as the home of the data management component of the SWOG Statistical Center, with a mission to help conquer cancer and other diseases using biostatistical principles and innovative data management methods. Cay became the original employee when CRAB’s first office opened in the Crowley’s basement in 1999. Sixteen years later, CRAB is a well-known research organization with more than 80 employees.

Over the years, Cay has served several administrative roles at CRAB. Having a doctorate in Developmental Psychology from the University of Washington served Cay well in taking on the many challenges that are a part of building an effective organization. After completing postdoctoral training in clinical psychology at University of Wisconsin, Cay practiced in Wisconsin before moving to Seattle where she co-founded Northwest Psychological Services. Cay says that her training and business experience provided her with many of the skills she has used at CRAB.

Serving over the years as Chief Administrative Officer, Chief Operations Officer, and Chief Financial Officer, Cay performed the usual tasks associated with the titles and many others that fall under “other duties, as assigned,” always included in her job descriptions. Cay led the development of sound administrative, financial, and human resources policies and procedures. Regulations don’t always make it easy to produce policies that are consistent with making CRAB a great place to work, but Cay worked diligently to strike a balance. Recently, Cay completed comprehensive revisions to our policies and procedures, and was instrumental in the design of the SharePoint site where the documents are now stored.

For many years, Cay was responsible for the development and maintenance of CRAB's strategic plan. As a corporate officer, Cay served as a CRAB Vice President, with Board-defined roles as Secretary and Treasurer, and she spent many years as the primary liaison with the Board of Directors. Cay was also CRAB’s chief Annual Report and newsletter writer.

Cay’s financial stewardship has been demonstrated in the development of an excellent Finance team who follow sound policies and procedures that have consistently resulted in clean audits and accurate budgeting, and in the development of a reserve fund and the creation of a rich benefit package for employees.

Included among Cay’s roles is the acquisition of office space, facilities, and equipment to meet the technology needs associated with biostatistical analyses. In 2007, Cay led an effort to obtain support for a high dimensional genomic and proteomic data to support cancer biology research and clinical trials. Support to purchase the system of servers and disk storage came from the Myeloma Institute for Research and Therapy (MIRT), MJ Murdock Charitable Trust, and the Seattle Foundation.

CRAB has grown over the years and Cay has overseen moves from the Crowley basement to the Metropolitan Park West building in downtown Seattle and across the street to the Metropolitan Park East building. In 2009, Cay completed negotiations on an affordable 10-year lease. In 2010, Cay had oversight of a remodel of the two floors that CRAB occupies, including all new network cabling, functional meeting spaces, and a modern computer data center with a cooling system independent of the building’s system, a new power supply with battery backup, and a sprinkler system that is charged with water only in the event of a fire. The new lease ensures that CRAB remains at Met Park East into April, 2020.

Throughout her career Cay has been the consummate team player, providing support for many collaborative efforts to implement John Crowley’s vision to form CRAB into a leading cancer research center. Cay’s financial management, administrative oversight, and organizational efforts supported the work of many at CRAB in the accomplishment of important projects.

Chief Executive Officer Dr. John Crowley, making his own transition in 2015 to Chief of Strategic Alliances, said, “Cay’s many contributions have been vital to CRAB’s growth as an effective research organization. I wouldn’t have started CRAB if I wasn’t sure that I could trust Cay to do whatever was required for us to succeed as an organization.”

As CRAB’s co-founder, Cay will continue to contribute through her legacy and support. Supplied with a permanent key card to CRAB offices, she will continue to be sought out for advice when she’s in the building. Cay’s next job description isn’t written yet, but it’s sure to include new challenges and adventures and the quintessential other duties, as assigned, with one important distinction. For her new job description, Cay said, “I’ll be the one assigning the other duties.”


CRAB Networks with Survivors

March 31, 2015 -- CRAB continues to engage with the local community of cancer survivors and patient allies. CRAB was honored to host presentations on cancer survivorship and patient advocacy, given by Anna Gottlieb, Director of Gilda's Club Seattle and two survivors: Ann Colliers, RN and her daughter Katie Colliers, a University of Washington Junior and Huskies Women's Basketball player. Ann and Katie shared her story of surviving breast cancer and Katie is a survivor of leukemia. The event, attended by CRAB employees and Board of Directors members, featured information on CRAB's plans to create a survivorship website in collaboration with SWOG.

Lunch, smiles and a few tears were shared. Larry Kaye (Data Coordinator) called Ann and Katie "extraordinary cancer survivors, truly inspirational...[their story] makes me proud to work in non-profit cancer research". Pingping Qu (Senior Biostatistician) said "it was a great session...I admit I had to use some kleenex myself". Grace Powell (Regulatory Affairs/QA Manager) called the event "another reminder of why we do what we do!"