Research > Statistical Tools
Through collaboration between biostatisticians at SWOG and CRAB, we have developed calculators to address statistical needs such as clinical trial design, probability distributions, expected number of events for a given timeframe and exact confidence interval generation. Sample size requirements can be quickly derived for specified levels of error (Type 1 and Type 2) for one-sample and two-sample designs. Alternatively, for a given sample size and alpha-level, statistical power can be readily calculated.
The calculators support designs with binomial, continuous and time-to-event endpoints. Non-inferiority designs for time-to-event endpoints are also available.
These calculators have been used for many years in support the design of SWOG trials and other investigator-initiated and registration trials.
These tools are hosted at https://stattools.crab.org/.