About CRAB > Management Team
The Officers of Cancer Research And Biostatistics bring a myriad of skills and talents honed through years of experience in cancer research, clinical trials, and product development. Our leadership team has experience working with publicly funded clinical trial consortia such as SWOG, but we also work with universities, research institutes, pharmaceutical partners, biotech companies. Collectively this team oversees the day to day leadership and operations of CRAB, and work closely with the clinicians seeing patients.
Antje Hoering, Ph.D.
William S. Charters, M.B.A.
Curt Malloy, J.D., M.P.H.
Keith Goodman, D.B.A.
John Crowley, Ph.D.
Antje Hoering, Ph.D. is President and Chief Executive Officer of Cancer Research And Biostatistics (CRAB). She leads and oversees a team that includes biostatisticians, programmers, IT engineers, program managers, data coordinators, and medical monitors providing a full suite of CRO services in oncology. Dr. Hoering also serves as the Consortium Principal Investigator (PI) for two NIH grants that provide support for the SWOG Cancer Research Network, the NCI’s National Clinical Trials Network NCTN Clinical Research Cooperative Agreement and the NCI public-private Lung-MAP partnership. She is the lead statistician of the SWOG Myeloma Committee and an active member of the NCI Myeloma Steering Committee and the Pediatric Lymphoma and Leukemia Committee. Dr. Hoering serves as the Independent Analysis Center PI for a Friends of Cancer Research sponsored collaboration (ctMoniTR) with leaders across multiple healthcare sectors and disciplines to investigate circulating tumor DNA as a potential monitoring tool to evaluate a patient’s response to treatment. Antje previously had a long-standing collaboration at the UAMS Myeloma Institute in which she began as a co-investigator and advanced to the role of Biostatistical Core Director. She and her team continue to work with UAMS Myeloma Institute on a consulting basis.
Dr. Hoering is an associate editor of the Statistics in Biopharmaceutical Research and co-editor of the third edition of the Handbook of Statistics in Clinical Oncology. She has led several workshops nationally and internationally on biostatistical principals in oncology clinical trials for a variety of audiences. Dr. Hoering holds affiliate faculty appointments at the Fred Hutchinson Cancer Research Center and the Biostatistics Department of the University of Washington.
Before joining CRAB, Dr. Hoering was a senior research associate at the Cancer Center at the Mayo Clinic, and an Assistant Professor at the Mayo Medical School in Rochester, Minnesota. Dr. Hoering obtained her PhD in physics from the Max-Planck-Institute for Nuclear Physics in Heidelberg, Germany. She transitioned into biostatistics as an NIH post-doctoral fellow at the Biostatistics Department of the University of Washington and the Fred Hutch Cancer Research Center. She is a 2017 graduate of the Executive Development Program at the Foster Business School at the University of Washington.
William Charters, Vice President, Treasurer, and Chief Financial Officer, guides the fiscal direction of CRAB while it seeks to expand current and future collaborations with cancer centers, clinical research consortia, private industry, and non-profit groups involved in oncology clinical trials.
Mr. Charters leads CRAB’s Finance, Human Resources, and Regulatory Compliance/Quality Assurance Departments overseeing the strategies, policies and procedures of each department assuring adherence to specific regulations including Generally Accepted Accounting Principles (GAAP), Federal Grant Regulations (OMB A-133) and Not for Profit Cost Principals (A-122) as well as Human Resources practices, policies and procedures assuring adherence to federal, state and local employment laws and guidelines. In addition, Mr. Charters provides oversight of regulations governing the activities at CRAB, including Good Clinical Practices, 21CFR Part 11, Protection of Human Subjects, Professional Conduct (Conflict of Interest, Fraud) and regulations specific to our collaborators such as best practices related to HIPAA.
Mr. Charters comes to CRAB with 30 years of experience in leadership and business operations developed within the contract research organization, Battelle, where he served as financial manager implementing financial and operational initiatives in support of strategic objectives focused on improving public health and data analytics, working with government and commercial clients to accelerate innovation in health and life sciences. Most recently, Mr. Charters was the Finance Manager for Battelle’s Health and Analytics business unit, where he lead center business activities; implemented operational plans and budgets, monitored financial metrics and key indicators to achieve financial objectives.
Mr. Charters holds an MBA from the Gonzaga University School of Business and earned his Bachelor’s in Business Administration from Seattle University. He enjoys traveling with his wife Marcie and other activities, including fly-fishing, skiing, rowing, and furniture-building. He is a member of Western Rivers Conservancy and Lake Union Crew.
Keith Goodman, D.B.A., Vice President and Chief Technology Officer, leads the Applications Development and Information Technology departments in the development of cutting-edge data capture solutions and the support of technology services that ensure the availability and protection of clinical trial data. He also oversees the Administrative Services department. Dr. Goodman joined CRAB in November 2005 and has served as CTO since January 2008 when he became a member of the management team.
Dr. Goodman has more than 25 years of experience in computer technology, including roles in application development, business management, and computer systems support. His expertise in software development and corporate management is honed from 10 years leading his own software development company, NRSPACE Software, which created applications focused on training nurses and healthcare technicians. Following an initial career as a journalist when he also became an ad-hoc computer technician, Dr. Goodman’s technology career formally began at the Fred Hutchinson Cancer Research Center where he supported research computer systems.
Dr. Goodman holds a Doctorate in Business Administration from Argosy University/Seattle and Bachelor’s and Master’s degrees in Communications from the University of Washington. His research interests include automating the capture of data from electronic medical records for use in in multisite cancer clinical trials. Keith enjoys reading for personal growth and pleasure, traveling, hiking, fishing, and watching and coaching baseball.
In his role as Chief Operating Officer, Curt oversees data operations, enterprise operations and works in tandem with John Crowley to accelerate clinical trial site development in Latin America.
Mr. Malloy has led operational activities in several non-profit organizations in Seattle, to include the Infectious Disease Research Institute, where he served as Senior Vice President of Operations and General Counsel – and most recently with the Fred Hutchinson Cancer Research Center, where he served as operations leader of the Vaccine and Infectious Disease Division.
Mr. Malloy’s professional interests include the impact of both infectious and chronic diseases in the developing world. He is fascinated with product development in all its complexity and risks, fully understanding the extraordinary public health benefit of developing novel therapies and prophylactic innovations. Curt has also taught and lectured on the role of intellectual property in technology development to reduce the global burden of disease.
Curt is fluent in Spanish, having worked as a health promoter in Quetzaltenango, Guatemala and as a consultant in occupational epidemiology in Puerto Rico. Curt is an adjunct professor at Seattle University, where he has taught in the College of Arts and Science, the School of Law, and the College of Nursing. He is also currently board chair for the Washington Global Health Alliance.
Curt received a Bachelor of Arts in Chemistry and Computer Science at Pacific Lutheran University, a Masters of Public Health from Columbia University School of Public Health, and a Juris Doctor from Seattle University School of Law.
John Crowley, Ph.D., brings four decades of experience in Biostatistics to his role as Chief of Strategic Alliances. Dr. Crowley founded CRAB in 1997, and served as President and CEO until 2014. Dr. Crowley was the Director of the Statistical Center for SWOG, co-located at CRAB and the Fred Hutchinson Cancer Research Center from 1984 to 2012.
Dr. Crowley's research interests focus on the design and analysis of cancer clinical and translation trials. His more recent research focuses on analytical methods for utilizing microarray data to determine predictive and prognostic groups; the design of targeted therapy trials; and methods for describing staging systems for lung cancer and myeloma. His longstanding interest in developing exploratory tools for survival data has produced widely used statistical applications in these areas. Dr. Crowley also educates cancer clinicians and biostatisticians nationally and locally in the principles and pitfalls of cancer clinical trials.
Since Dr. Crowley's research career began in 1974, he has had numerous significant accomplishments. He served as Head of the Biostatistics Program at the Fred Hutchinson Cancer Research Center from 1983 until 1993, during which time he was honored with a Mortimer Spiegelman Award, given every year by the American Public Health Association to an outstanding young biostatistician. Dr. Crowley's credentials also include prestigious fellowships from the American Statistical Association and the Society for Clinical Trials, the Marvin Zelen Award for Leadership in Statistical Science, and the Breslow Lectureship. To date Dr. Crowley has authored over 400 professional papers and books.
Dr. Crowley received his master’s and doctorate degrees in Biomathematics from the University of Washington. He served as a Postdoctoral Fellow at Stanford University. Moving to the University of Wisconsin, Dr. Crowley was appointed Assistant Professorship, followed by an Associate Professorship in the Departments of Human Oncology and Statistics. In 1982 Dr. Crowley accepted an appointment as Associate Member at the Fred Hutchinson Cancer Research Center along with an Associate Professorship in Biostatistics at the University of Washington. He was subsequently promoted to Full Professor at the University and Full Member at Fred Hutch. Dr. Crowley’s academic base is now at CRAB. John is an avid sports fan, and enjoys traveling, hiking and bird watching.