CRAB provides the statistical and operational support required by Data Monitoring Committees (DMCs) or Data Safety Monitoring Boards (DSMBs)
An Independent Statistical Center (ISC) creates and presents in-depth and insightful analyses and reports to support the DMC in a manner that assures timely decision-making.
CRAB Biostatisticians have decades of experience serving in this role and have also acted as well as members of the DMC. This experience has informed our approach to create well-organized and comprehensive reports and by responding quickly to the needs of the DMC.
CRAB ensures data and documentation are securely stored and transferred. Access to the data and documentation is restricted by role in the DMC and securely managed by a CRAB Sponsored Secure-FTP or through compliant software.
CRAB Project Managers aid in facilitating efficiency in operational activities of the DMC and ISC, including by coordinating and scheduling meetings with all DMC members; distributing all meetings documents before and after meetings, as per DMC charter; managing timesheets and payments of DMC Members; and liaising between the ISC, the DMC and the Sponsor.
We also participate in creating or reviewing the DMC charter; programming tables, listings, and figures; analyzing and interpreting data related to efficacy, safety, study conduct and interim analyses; and preparing and presenting reports for open and closed-session meetings.