Your Research Partner in the Fight Against Cancer

Cancer Research And Biostatistics is a non-profit organization whose purpose is to help conquer cancer and other diseases using the tools and expertise we bring to oncology clinical development.

Featured Services

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Biostatistics

We conduct phase I through phase III multi-institutional trials. The design and analysis of a wide variety of oncology clinical trials constitutes the majority of our work. Trials range from Phase I single or multi-institution industry sponsored to Phase III multi-institutional trials.
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Electronic Data Capture (EDC)

CRAB has extensive experience in developing software solutions to support data collection for clinical trials. Our CRAB Nebula™ system include technologies to securely capture, store, analyze and report data.

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Data Management

Data collection, management and quality are our top priority. At CRAB, we believe the collection, monitoring and management of data are crucial to quality research and science.

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Our Expertise

Clinical Trial Expertise from Statistics to Data Collection and Management

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Founder John Crowley and CEO Antje Hoering

CRAB was founded 25 years ago to play a unique and critical role in the battle against cancer.

Our commitment to prevent and cure cancer is reflected in our approach to clinical research. As a nonprofit organization focused on cancer research, we provide accurate, timely, objective, independent results to our clients.

CRAB has a team of dedicated, talented statisticians, project managers, data monitors, application developers, and regulatory affairs personnel who provide the expertise to fulfill our mission and serve our clients.

Graphic of CRAB expertise by cancer type

Latest News

CRAB Collaborates with FoCR on ctDNA Work

August 3, 2023

Friends of Cancer Research work on ctDNA focuses on collaboratively establishing evidence to support the use of ctDNA as an early endpoint. Cancer Research And Biostatistics (CRAB) serves as the independent analysis center for this project and as such we are responsible for all the analyses. CRAB is incredibly proud to be part of this […]

CRAB Edits Fourth Edition of the Handbook of Statistics in Clinical Oncology

July 3, 2023

Cancer Research And Biostatistics (CRAB) founder John Crowley, PhD and CRAB CEO, Antje Hoering, PhD, were invited by Taylor & Francis Group to serve as editors for the Fourth Edition of the Handbook of Statistics in Clinical Oncology. For this fourth edition, Megan Othus, PhD, from the Fred Hutch will join the editorial team. Many […]

Pragmatica-Lung Trial (S2302)

February 3, 2023

Cancer Research And Biostatistics (CRAB) is excited to be a part of the Pragmatica-Lung trial (S2302) which is set to be activated by 2/27/23. The S2302 Pragmatica-Lung trial is a phase 3 follow-up trial to Lung-MAP. S2302 is a new approach to clinical trials with the intent to streamline the existing model of clinical trials […]

Partner with CRAB

CRAB's expertise in biostatistics, data management, application development and DMC statistical and meeting management provides reliable and defensible results for your clinical trial.

 

Research

CRAB has supported more than 300 adult clinical trials. Many of the trials conducted through CRAB have been in large-scale Phase III trials. We have expertise across all trial phases including multi-institutional Phase I trials. The other studies (15%) are comprised of biological correlative studies, registries, post-marketing trials and outcomes research. CRAB statisticians have decades of experience in the design and analysis of a wide variety of oncology clinical trials. 

Diagram of clinical trial experience by trial phase

Collaborations

CRAB achieves its mission through long-standing partnerships with both research collaborators and with for-profit organizations. The SWOG Statistics and Data Management Center (SDMC) is co-located at Fred Hutch and CRAB. SWOG is one of five U.S.-based National Cancer Institute-supported cooperative groups within the National Clinical Trials Network (NCTN). CRAB’s Clinical Research Services (CRS) division has a number of key partnerships with research consortia as well as pharmaceutical clients. Other important collaborations for CRAB are with Friends of Cancer Research (Friends) and the International Association For The Study Of Lung Cancer (IASLC).